Macitentan
Package | Price | Savings |
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Active ingredient | Macitentan |
Packaging Type | tablet |
Quantity per package | 629.92-989.93 |
Price of Macitentan | From USD 16.5 per tablet |
Dosage | 10mg |
Sale of Macitentan | without prescription |
In our online pharmacy, you can purchase Macitentan without a prescription. We guarantee a hassle-free shopping experience, providing access to quality medications conveniently and confidentially.
Occasionally, macitentan may be ineffective if the patient’s condition is unresponsive to therapy or due to drug interactions.
No, the contents of your Macitentan order are strictly confidential. All orders are securely packaged without any external markings revealing the contents, ensuring absolute discretion. We prioritize our customers’ privacy, and no third party will be informed about the details of your Macitentan order.
Macitentan is an endothelin receptor antagonist used to manage pulmonary arterial hypertension by relaxing blood vessels, improving blood flow and reducing blood pressure.
Yes, macitentan is FDA-approved in the USA for treating pulmonary arterial hypertension and is available by prescription.
Macitentan is an endothelin receptor antagonist that helps dilate blood vessels, reducing blood pressure and improving oxygen flow.
Macitentan typically begins to take effect within a few weeks, with full benefits realized over a period of several months.
Macitentan has a half-life of approximately 16 hours, with effects lasting well over a day, but individual responses can vary.
Misusing Macitentan may lead to liver problems, reduction in blood cell count, and harm to a fetus if taken during pregnancy. Always follow a doctor’s prescription.
Macitentan has a half-life of approximately 16 hours, but can take about 5 days to fully clear from your body.
Macitentan is not typically screened for in standard drug tests and is unlikely to cause a false positive for other substances.
Macitentan may interact with the following medications:
– Warfarin
– Simvastatin
– Ketoconazole
– Rifampin
– Cyclosporine
For detailed information and guidance, please contact our support team.
While moderate consumption of alcohol is generally not prohibited when taking Macitentan (Macitentan), it is always best to consult your healthcare provider. They can provide you with personalized advice based on your overall health condition, the dosage of the medication, and potential risks of interactions.
Macitentan is an oral medication typically taken once daily with or without food. The standard starting dose is 10 mg, and adjustments should be made by a healthcare provider based on clinical response and tolerability.
How to Take Macitentan |
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Take orally once daily with or without food |
Standard Dose |
10 mg |
Please consult with your healthcare provider for personalized dosing information and before starting any new medication.
Macitentan is a prescription medication designed for long-term treatment of pulmonary arterial hypertension under a doctor’s supervision. Always consult a healthcare provider for personalized advice.
In the rare case of an overdose of Macitentan, it is not usually considered potentially fatal. However, it is important to seek appropriate medical advice. If you suspect an overdose, you should:
Remember, responding quickly is crucial for managing the situation effectively without unnecessary alarms.
Macitentan, sold as Opsumit, directly targets the endothelin pathway, which is critical in treating pulmonary arterial hypertension (PAH). Its mechanism is distinctive due to its direct impact on this pathway. While it’s similar to bosentan (Tracleer), it differs in how it interacts with liver enzymes. Ambrisentan, found in Letairis, is also an endothelin receptor antagonist but is notable for its once-daily dosing convenience. Other medications such as Adcirca and Ventavis act on different mechanisms related to blood vessel dilation, while sildenafil (Revatio) and tadalafil (Adcirca) are PDE-5 inhibitors that focus on relaxing blood vessels in the lungs. Here is the table with the comparison information:
Pill | Active Component | Advantages and Differences |
---|---|---|
opsumit | macitentan | directly targets the endothelin pathway |
tracleer | bosentan | similar mechanism but affects liver enzymes differently |
letairis | ambrisentan | alternative endothelin receptor antagonist with once-daily dosing |
adalat, nifedipine | calcium channel blocker | not endothelin antagonist but can help PAH indirectly |
ventavis, iloprost, different class | inhaled therapy for PAH | dilates pulmonary blood vessels |
uptravi, selexipag | oral prostacyclin receptor agonist | another pathway for PAH treatment |
tyvaso, treprostinil | inhalable | works on prostacyclin pathway similar to selexipag but inhaled |
remodulin, treprostinil | subcutaneous/intravenous prostacyclin analog | longer half-life than iloprost |
revatio, sildenafil, PDE-5 inhibitor | works by relaxing blood vessels in lungs | similar purpose |
adcirca, tadalafil, another PDE-5 inhibitor | offers once-daily dosing for PAH | longer acting |
Before taking Macitentan, consult with your physician about potential side effects, interactions with other medications, and suitability if you have liver or kidney issues.
Macitentan is contraindicated in patients with hypersensitivity to the active substance or any of its excipients. It is not recommended during pregnancy due to potential harm to the developing fetus. Women of reproductive potential should use effective contraception during treatment.
Contraindications include:
– Hypersensitivity to macitentan or excipients
– Pregnancy
Macitentan is a medication used for the treatment of pulmonary arterial hypertension (PAH). Like all medications, it may cause side effects in some people, although not everyone experiences them. Common side effects are usually mild and may include symptoms like a runny nose or sore throat. However, it’s important to discuss any concerns with your healthcare provider to ensure the best possible treatment outcome.
Macitentan may be suitable for certain health conditions; consult your healthcare provider for advice on diet and physical activity compatibility.
Mental state may affect medication adherence, but Macitentan’s efficacy primarily hinges on its pharmacological action on pulmonary arterial hypertension, not psychological factors.
Consult a doctor before taking Macitentan if you have liver issues, are pregnant, or planning to conceive, as it may cause harm to the fetus. Additionally, seek medical advice immediately if you experience symptoms such as difficulty breathing, swelling, or skin rashes while using Macitentan.
In our pharmacy, Macitentan is available at the most competitive price, ensuring value for your money compared to others. While other stores offer quality, our exclusive offers ensure that you receive first-class medicines without paying too much. Buy from us and experience the perfect combination of affordability and reliable quality.
Macitentan is available for delivery to the following cities in the USA:
City | Region | Delivery time |
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New York | New York | 5-7 days |
Los Angeles | California | 5-7 days |
Chicago | Illinois | 5-9 days |
Houston | Texas | 5-9 days |
Phoenix | Arizona | 5-9 days |
Philadelphia | Pennsylvania | 5-9 days |
San Antonio | Texas | 5-9 days |
San Diego | California | 5-9 days |
Dallas | Texas | 5-9 days |
San Jose | California | 5-9 days |
Austin | Texas | 5-9 days |
Jacksonville | Florida | 5-9 days |
San Francisco | California | 5-9 days |
Columbus | Ohio | 5-9 days |
Indianapolis | Indiana | 5-9 days |
Fort Worth | Texas | 5-9 days |
Charlotte | North Carolina | 5-9 days |
For additional locations and questions about deliveries, please contact our support team.